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Erkki Ruoslahti was born on 16 February, 1940 in Imatra, Finland, is an Erkki Ruoslahti is cancer researcher. Discover Erkki Ruoslahti's Biography, Age, Height, Physical Stats, Dating/Affairs, Family and career updates. Learn How rich is he in this year and how he spends money? Also learn how he earned most of networth at the age of 84 years old?

Popular As N/A
Occupation N/A
Age 84 years old
Zodiac Sign Aquarius
Born 16 February 1940
Birthday 16 February
Birthplace Imatra, Finland
Nationality Finland

We recommend you to check the complete list of Famous People born on 16 February. He is a member of famous researcher with the age 84 years old group.

Erkki Ruoslahti Height, Weight & Measurements

At 84 years old, Erkki Ruoslahti height not available right now. We will update Erkki Ruoslahti's Height, weight, Body Measurements, Eye Color, Hair Color, Shoe & Dress size soon as possible.

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Dating & Relationship status

He is currently single. He is not dating anyone. We don't have much information about He's past relationship and any previous engaged. According to our Database, He has no children.

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Erkki Ruoslahti Net Worth

His net worth has been growing significantly in 2023-2024. So, how much is Erkki Ruoslahti worth at the age of 84 years old? Erkki Ruoslahti’s income source is mostly from being a successful researcher. He is from Finland. We have estimated Erkki Ruoslahti's net worth, money, salary, income, and assets.

Net Worth in 2024 $1 Million - $5 Million
Salary in 2024 Under Review
Net Worth in 2023 Pending
Salary in 2023 Under Review
House Not Available
Cars Not Available
Source of Income researcher

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Timeline

1940

Erkki Ruoslahti (born 16 February 1940 in Imatra, Finland) is a cancer researcher and distinguished professor at Sanford Burnham Prebys Medical Discovery Institute.

1965

Ruoslahti received his M.D. from the University of Helsinki in 1965 and his Ph.D. from the same institution in 1967.

He completed postdoctoral studies at Caltech.

1976

He moved from Finland to the United States in 1976.

Ruoslahti made seminal contributions to biology of extracellular matrix and its receptors.

He was one of the discoverers of fibronectin, an adhesion molecule and component of extracellular matrices, and he subsequently identified and cloned a number of other extracellular matrix components and adhesion molecules.

1979

Ruoslahti held various academic appointments with the University of Helsinki and the University of Turku in Finland and City of Hope National Medical Center in Duarte, California until joining the La Jolla Cancer Research Foundation (now Sanford Burnham Prebys Medical Discovery Institute, or SBP) in 1979.

1984

In 1984, he identified the sequence within fibronectin that mediates cell attachment, called RGD for the amino acids of which it’s composed, and isolated the cellular receptors that bind that sequence, now known as integrins.

The RGD discovery has led to the development of drugs for vascular thrombosis and cancer, among other diseases.

Ruoslahti currently studies specific marker molecules in blood vessels.

He introduced the concept of vascular "zip codes," the idea that each tissue bears molecular signatures that can be targeted by affinity ligands, and used in vivo peptide phage display to prove the concept and develop numerous tumor-homing peptides.

1989

He served as SBP's president from 1989-2002, and was a distinguished professor at the University of California, Santa Barbara from 2005-2015.

Ruoslahti's research group has developed a novel class of tumor-homing peptides that can be used to enhance delivery of drugs and nanoparticles to tumors.

These tumor-penetrating peptides selectively home to tumor vessels, where they activate a transport pathway that delivers the peptide, and along with it drugs and even nanoparticles, through the wall of tumor blood vessels and deep into tumor tissue.

Having bound to tumor vessels the peptide is cleaved and an amino acid sequence motif named the C-end rule or CendR motif (pronounced "sender") is exposed at the C-terminus of the peptide.

Subsequent binding of the peptide to neuropilin-1 activates the CendR transport pathway into and through tumor tissue.

The prototype tumor-penetrating peptide, iRGD, is in clinical trials in solid tumor patients tested as an enhancer of cancer therapies.

This peptide recognizes many different types of cancers, and it can be used for tumor delivery of various payloads that are either coupled to the peptide, or given together with it.

iRGD has also been shown to effectively deliver drugs to the placenta, which could aid in the treatment of slow fetal growth.

Recently, in vivo phage screening has been used to identify peptides that target hypertensive pulmonary arteries, atherosclerosis, and diseases of the brain.